Stimuli sensitive hydrogels for ophthalmic drug delivery: A review
نویسندگان
چکیده
منابع مشابه
Stimuli Sensitive Hydrogels in Drug Delivery Systems
Hydrogels are the 3 dimensional cross linked polymeric networks which absorb the water 10-20 times of its molecular weight. Hydrogels are sensitive to different environmental stimuli like pH, temperature, ion, electric signals, light, pressure, antigen specific, enzyme sensitive, and glucose levels. When the environment is get change they get swell, and swelling is the most important characteri...
متن کاملAn Overview - Stimuli Sensitive Hydrogels in Ocular Drug Delivery System
The aim of this review is to explore the advanced progress of ophthalmic products; drug delivery is one of the mainly tricky and complicated fields for researchers. The conventional formulations such as solutions, suspensions, ointments, etc. shows some constraint in increase of pre-corneal elimination, elevated changeability in efficiency, blurred vision and also diminish their bioavailability...
متن کاملEnvironment-sensitive hydrogels for drug delivery.
Environmentally sensitive hydrogels have enormous potential in various applications. Some environmental variables, such as low pH and elevated temperatures, are found in the body. For this reason, either pH-sensitive and/or temperature-sensitive hydrogels can be used for site-specific controlled drug delivery. Hydrogels that are responsive to specific molecules, such as glucose or antigens, can...
متن کاملOphthalmic Drug Delivery in Glaucoma—A Review
Glaucoma is a progressive optic neuropathy and medical therapy is the initial option for the treatment of this potentially blinding condition. Topical instillation of eye drops from the bottle is the most common glaucoma drug delivery form. Due to limited permeability of anterior ocular surface, natural clearance and drainage, eye drops contain large amounts of inactive ingredients. Effective p...
متن کاملOphthalmic Drug Delivery Systems for Antibiotherapy—A Review
The last fifty years, ophthalmic drug delivery research has made much progress, challenging scientists about the advantages and limitations of this drug delivery approach. Topical eye drops are the most commonly used formulation in ocular drug delivery. Despite the good tolerance for patients, this topical administration is only focus on the anterior ocular diseases and had a high precorneal lo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Pharmaceutical Investigation
سال: 2012
ISSN: 2230-973X
DOI: 10.4103/2230-973x.100036